Mientras existe evidencia que sugiere que el uso de antioxidantes disminuye los efectos secundarios propios del tratamiento contra el cáncer, hay datos que sugieren que los antioxidantes incrementan el riesgo de recurrencia de cáncer por la afectación de la terapia de los tratamientos. Introducción y objetivos: la terapia con antioxidantes durante la quimioterapia y radioterapia en pacientes con cáncer cervicouterino es controvertida. A different dosage may have the expected effect however, further studies with another dosage and criteria are necessary.Ĭonclusions: Supplementation with antioxidants during treatment of cervical cancer has no effect on cancer recurrence after 4 years of follow-up. Regarding implications of cancer survivors, antioxidant supplementation apparently seems not to have interference with recurrence in cervical cancer patients but there is not enough evidence to prove it. 8% (n = 7) patients were in the antioxidant group and 15.9% (n = 14) were in the placebo group (p > 0.05). Of the original 103 patients, were able to follow up on 88 patients for an additional four years.23.9% (n = 21) of the patients presented cancer recurrence and 76.1% (n = 67) did not, 21.6% (n = 19) patients showed metastasis. Results: 103 treated patients were in clinical stages IIB and IIIB of cervical cancer, 48% (n = 49) of the patients were treated with antioxidant supplementation and 52% (n =54) of the patients were in the placebo group. Survival was calculated by the Multivariate COX regression with omnibus test and the enter method. Differences between groups were analyzed using chi-square test. We also conducted data on used hemoglobin and albumin levels. Methods: We conducted a controlled clinical trial in cervical cancer patients supplemented with an antioxidant mixture or a placebo during four years after their antineoplastic treatment was completed and the effect on recurrence. While some evidence suggests that the use of antioxidants diminishes side effects from anticancer therapy, there is also data to suggest that antioxidants increase the risk of recurrence by affecting oncology treatments. Introduction and aim: Antioxidant therapy with chemotherapy and radiotherapy in cervical cancer patients is controversial. Universidad Popular Autónoma del Estado de Puebla. Karolina Álvarez-Altamirano 1, Alma Nubia Mendoza-Hernández 2, Carolina Carcoba-Tenorio 3, José Antonio García-García 1 and Vanessa Fuchs-Tarlovsky 1ĢFacultad de Nutrición. La suplementación con antioxidantes durante el tratamiento oncológico no tiene efecto sobre la recurrencia de cáncer cervicouterino TRABAJO ORIGINAL / Epidemiología y dietéticaĪntioxidant supplementation during oncology treatment has no effect on cervical cancer recurrence
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